ABSTRACT
Most cases of SARS-CoV-2 infection are asymptomatic or have only mild respiratory symptoms. Patients with risk factors, including but not limited to advanced age, obesity, cardiovascular diseases and immunosuppression, may develop a severe course of disease due to the development of a cytokine storm. COVID-19 is associated with an increased risk of bleeding and thromboembolic complications, with the gastrointestinal tract and CNS being among the most frequent sites of bleeding. One of the causes of vessel wall rupture and subsequent bleeding in COVID-19 may be dysfunction of the damaged endothelium. Viral infections are one of the most potent triggers of autoimmune diseases. One of the possible causes of haemorrhagic stroke is virus-induced acute vasculitis.
ABSTRACT
The COVID-19 pandemic in 2020 affected the whole world. According to the World Health Organization (WHO), more than 140 million people worldwide have been infected and over 3 million people have died. COVID-19 has affected medicine, education, economics and social life. COVID-19 is caused by the SARS-CoV-2 coronavirus. It belongs to the family Coronaviridae. Six other coronaviruses are known to cause respiratory disease in man. The association between viral diseases and autoimmune diseases is well known, although the exact mechanisms remain unclear. Even the SARS-CoV-2 coronavirus can cause various autoimmune disorders, including type 1 diabetes mellitus. At the University Hospital in Hradec Kralove, we diagnosed new-onset diabetes mellitus in four young patients. © 2021 TIGIS Spol. s.r.o.. All rights reserved.